Advanced Biophysical Approaches to Nano-Bio-Sensing
Fabio Domenici
Broschiertes Buch

Advanced Biophysical Approaches to Nano-Bio-Sensing

Potential Environmental and Biomedical Applications Based on p53-Azurin Interaction

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Nano-bio-sensing based on plasmonics is now entrenching in environmental and biomedical fields, thus opening to the possibility of providing new anticancer strategies. This work is devoted to the exploration of the interaction between p53 and Az. p53 is a valuable indicator of cancer cells and can be recognized by Az even enhancing its tumour suppressor activity. The analytical potential of plasmonics has been addressed in the attempt to overcome detection limits of Raman and Absorbance spectroscopies. Surface-enhanced Raman spectroscopy, also combined with AFM, provided an approach to improve...