The Biology of Cancer is a new textbook for undergraduate and
graduate biology students as well as medical students studying the
molecular and cellular bases of cancer. The book presents the
principles of cancer biology in an organized, cogent, and in-depth
manner. The clarity of writing and the lucid full-colour art
program make the book accessible and engaging. The information
unfolds through the presentation of key experiments which give
readers a sense of discovery and provide insights into the
conceptual foundation underlying modern cancer biology.
The Biology of Cancer synthesizes the findings of three decades of
recent cancer research and proposes a conceptual framework from
which to teach about these discoveries. It provides the necessary
structure, organization, and content for a course on cancer biology
for advanced undergraduates and beginning doctoral students. The
book is comprehensive and offers many pedagogical features to
assist teaching and learning. The book includes many recent and
topical references to empower the student to move directly into the
primary research literature.
The text is up-to-date and provides current information on topics
such as tumour stem cells and recently introduced
chemotherapeutics. State-of-the-art techniques are discussed
throughout. Modern biomedical research is explored, helping readers
to hone their analytical abilities and to assimilate and think
clearly about complex biological processes. The Biology of Cancer
will provide insights into many aspects of immunology,
developmental biology, and neurobiology.
The book is extensively illustrated with carefully chosen schematic
drawings, micrographs, computer-generated models and graphs to
support and clarify the concepts, as well as to supply additional
interest. The exceptional full-colour art program contains many
images from recent research literature.
Besides its value as a textbook, The Biology of Cancer will be a
useful reference for individuals working in biomedical
laboratories, and for clinical professionals.
This is an impressively thoughtful, beautifully balanced analysis of where we stand today in the critical attempt to understand, and thereby defeat cancer as a scourge on humanity. Not only is it the perfect text for a serious course on cancer biology, it should be read by every cancer researcher - Bruce Alberts, University of California, San Francisco, USA The Biology of Cancer is no doubt the definitive statement on its topic today. -Science, 11 August 2006: Vol. 313. no. 5788 There is no comparable text in cancer biology and no single book that is so current and informative. -Nature, November 30, 2006, Vol 444 'The Biology of Cancer, written by the distinguished American cancer biologist Robert Weinberg, is by far the most extensive of these new works and, as the product of a single author, is a remarkable achievement. The book is beautifully illustrated in full colour and well supplied with key review articles. It is extremely well written in language that should be accessible to the non-expert. Overall, this is a remarkable achievement that is by far the most comprehensive coverage of this field available.' - The Times Higher Education Supplement, February 23rd 2007 "The breadth of the topics covered, the clear writing style, the logical organization and the beautiful figures make The Biology of Cancer a classic text for any biologist interested in cancer...An additional strength of the book is the multimedia CD...AThus, The Biology of Cancer is not only a great read but also an outstanding learning tool."-Nature Cell Biology (November 2007) vol. 9, no. 11
Dr. Robert A. Weinberg is a founding member of the Whitehead Institute for Biomedical Research and the Daniel K. Ludwig Professor for Cancer Research at the Massachusetts Institute of Technology (MIT). He is an internationally recognized authority on the genetic basis of human cancer. Dr. Weinberg and his colleagues isolated the first human cancer-causing gene, the ras oncogene, and the first known tumor suppressor gene, Rb, the retinoblastoma gene. The principal goal of his research program is to determine how oncogenes, their normal counterparts (proto-oncogenes), and tumor suppressor genes fit together in the complex circuitry that controls cell growth. More recently, his group has succeeded in creating the first genetically defined human cancer cells. He is particularly interested in applying this knowledge to improve the diagnosis and treatment of breast cancer. Dr. Weinberg is the author or editor of five books and more than 325 articles. His three most recent books, intended for a lay audience, are "One Renegade Cell", "Racing to the Beginning of the Road: The Search for the Origin of Cancer" and "Genes and the Biology of Cancer," co-authored with Dr. Harold E. Varmus, former Director of the National Institutes of Health. He is an elected Member of the U.S. National Academy of Sciences and Fellow of the American Academy of Arts and Sciences. Among Dr. Weinberg's many honors and awards are the Discover Magazine 1982 Scientist of the Year, the National Academy of Sciences/U.S. Steel Foundation Award in Molecular Biology, the Sloan Prize of the General Motors Cancer Research Foundation, the Bristol-Myers Award for Distinguished Achievement in Cancer Research, the Harvey Prize from the American Society for Technion Israel Institute of Technology, the Gairdner Foundation International Award, the Keio Medical Foundation Prize, the 1997 National Medal of Science, the City of Medicine Award and the 2004 Wolf Foundation Prize and the Prince of Asturias Science Prize. He has served on scientific advisory boards for the Institute of Molecular Pathology in Vienna, Austria, the Weizmann Institute in Rehovot, Israel, and the Massachusetts General Hospital in Boston. Born in Pittsburgh in 1942, Dr. Weinberg received his BS (1964) and PhD (1969) degrees in Biology from MIT. He did postdoctoral research at the Weizmann Institute and the Salk Institute in La Jolla, California, and then returned to MIT in 1972. In 1982, he was appointed Professor of Biology at MIT and also became one of the five original Members of the Whitehead Institute. He has been an American Cancer Society Research Professor at Whitehead and MIT since 1985.
1. The Biology and Genetics of Cells and Organisms 2. The Nature of Cancer 3. Tumor Viruses 4. Cellular Oncogenes 5. Growth Factors and their Receptors 6. Cytoplasmic Signaling Circuitry Programs Many of the Traits of Cancer 7. Tumor Suppressor Genes 8. pRb and Control of the Cell Cycle Clock 9. p53 and Apoptosis: Master Guardian and Executioner 10. Eternal Life: Cell Immortalization and Tumorigenesis 11. Multistep Tumorigenesis 12. Maintenance of Genomic Integrity and the Development of Cancer 13. Dialogue Replaces Monologue: Heterotypic Interactions and the Biology of Angiogenesis 14. Moving Out: Invasion and Metastasis 15. Crowd Control: Tumor Immunology and Immunotherapy 16. The Rational Treatment of Cancer
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Sehr gutes Buch. Sehr zu empfehlen für Diplom-Vorbereitung.
Sehr angenehm zu lesen, da der Erzählstil ziemlich gut ist und der Stoff nicht einfach nur trocken rübergebracht wird sondern auch kl. Geschichten zu den historischen Hintergründen eingebaut sind.