Sadettin Ozturk / Wei-Shou Hu (eds.)

Cell Culture Technology for Pharmaceutical and Cell-Based Therapies

Herausgeber: Ozturk, Sadettin; Hu, Wei-Shou

• Gebundenes Buch

Produktbeschreibung

This reference presents a comprehensive overview of the state-of-the-art in cell culture technology. The book describes manipulations and the genetic engineering of cells for the production of biotechnology products, tissue engineering, and cell-based therapies. Each expertly written chapter covers research, principles, and equipment currently affecting advances in the discovery of genes, host cell selection, cloning and gene amplification, bioreactor design, protein purification, optimization and scale-up, product quality, and facility design--showcasing the importance of genomic and cell-based technologies in the pharmaceutical industry.

Produktdetails

• Verlag: CRC Press
• Seitenzahl: 786
• Erscheinungstermin: 30. August 2005
• Englisch
• Abmessung: 262mm x 184mm x 40mm
• Gewicht: 1520g
• ISBN-13: 9780824753344
• ISBN-10: 0824753348
• Artikelnr.: 21627236

Autorenporträt

Wei-Shou Hu, Sadettin Ozturk

Inhaltsangabe

Preface. Cell Culture Technology: An Overview. Recombinant DNA Technology
and Cell Line Development. Medium Development. Cell Metabolism. Protein
Glycosylation. Cell Culture Bioreactors. Aeration, Mixing and Hydrodynamics
in Bioreactors. Instrumentation and Process Control. Cell Culture Kinetics
and Modeling. Fed-Batch Cultivation Of Mammalian Cells For Production Of
Recombinant Proteins. Optimization of High Density Perfusion Bioreactors.
Cell Separation And Product Capture. Downstream Processing. Formulation,
Finishing, and Packaging. Validation Of Cell Culture Based Processes &
Qualification Of Associated Equipment And Facility. Facility Design.
Transient Expression of Proteins. Large-Scale Propagation of Insect Cells.
Advances In Adult Stem Cell Culture. Ex Vivo Culture Of Hematopoietic And
Mesenchymal Stem Cells For Tissue Engineering And Cell-Based Therapies.