Personalized Nutrition for the Diverse Needs of Infants and Children

Personalized Nutrition for the Diverse Needs of Infants and Children

Research has shown that humans respond differently to diets and, moreover, that they display varying predispositions to many diet-dependent metabolic and degenerative diseases. The focus of nutritional science is thus shifting from dietary guidelines for populations to individualized foods and diets. It is the aim of nutrigenomics to assign this human diversity in nutritional response to diet - as well as the subsequent consequences to human health - to specific genetic elements. At the same time, evidence suggests that diet itself is a critical determinant of human diversity.This publication focuses on the differences of humans as infants and children with respect to nutritional needs and responses to diet. For this purpose, four main points are discussed, namely 1) How do children differ in view of genetic diversity, environmental inputs, prior imprinting, and resident microflora; 2) What are the immediate and long-term consequences of these differences; 3) Can we accurately assess them; and 4) How can we act on these differences.Supplying answers to some crucial issues, as well as identifying directions for further research and practical applications by the food industry, this publication is an important source of information for all those involved in the subject of diet and individual responses.

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Inhaltsangabe

Preface
Foreword
Contributors
Biological Diversity in Human Infants
Developmental Perspectives on Individual Variation: Implications for Understanding Nutritional Needs: Gluckman, P.D.
Beedle, A.S.
Hanson, M.A.
Yap, E.P.
Factors Influencing the Establishment of the Intestinal Microbiota in Infancy: Adlerberth, I.
Genetically Determined Variation in Polyunsaturated Fatty Acid Metabolism May Result in Different Dietary Requirements: Koletzko, B.
Demmelmair, H.
Schaeffer, L.
Illig, T.
Heinrich, J.
Assessment Technologies for Human Infant Health
Discussion on '(Molecular) Imaging: Developments Enabling Evidence-Based Medicine': Hofstraat, H.
Metabolic Profiling: Berry, G.T.
Newborn Screening of Metabolic Disorders: Recent Progress and Future Developments: Rinaldo, P.
Lim, J.S.
Tortorelli, S.
Gavrilov, D.
Matern, D.
Health Challenges of Human Infants
The Phenotype of Human Obesity: The Scope of the Problem: Bier, D.M.
Intestinal Immune Health: Conroy, M.E.
Walker, W.A.
Gut Decontamination with Norfloxacin and Ampicillin Enhances Insulin Sensitivity in Mice: Chou, C.J.
Membrez, M.
Blancher, F.
Individual Epigenetic Variation: When, Why, and So What?: Gomes, M.V.
Waterland, R.A.
Interaction of Early Infant Feeding, Heredity and Other Environmental Factors as Determinants in the Development of Allergy and Sensitization: Savilahti, E.
Personalized Care of Pediatric Cancer Patients: Rabin, K.
Man, T.-K.
Lau, C.C.
Opportunities for Improving Human Infant Nutrition and Health
Personalizing Nutrient Intakes of Formula-Fed Infants: Breast Milk as a Model: Lonnerdal, B.
Human Milk Oligosaccharides: Evolution, Structures and Bioselectivity as Substrates for Intestinal Bacteria: German, J.B.
Freeman, S.L.
Lebrilla, C.B.
Mills, D.A.
Opportunities for Improving the Health and Nutrition of the Human Infant by Probiotics: Salminen, S.
Isolauri, E.
Do We Need Personalized Recommendations for Infants at Risk of Developing Disease?: Hernell, O.
West, C.
Concluding Remarks.